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Physiologically Relevant Structure of Alzheimer's Related Amyloid Protein and the Role of Embedded Water in Its Amphiphilc Pore

✍ Scribed by Ghatty, Pavan K.

Book ID: 122367031
Publisher: Biophysical Society
Year: 2014
Tongue: English
Weight: 39 KB
Volume: 106
Category: Article
ISSN: 0006-3495
DOI: 10.1016/j.bpj.2013.11.1329

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## Abstract The neuropathological features associated with Alzheimer's disease (AD) brain include the presence of extracellular neuritic plaques composed of amyloid β protein (Aβ), intracellular neurofibrillary tangles containing hyperphosphorylated tau protein, and the loss of basal forebrain chol