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Physiologically based pharmacokinetic models for everolimus and sorafenib in mice

โœ Scribed by Pawaskar, Dipti K.; Straubinger, Robert M.; Fetterly, Gerald J.; Hylander, Bonnie H.; Repasky, Elizabeth A.; Ma, Wen W.; Jusko, William J.

Book ID
120156852
Publisher
Springer
Year
2013
Tongue
English
Weight
340 KB
Volume
71
Category
Article
ISSN
0344-5704

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## Abstract Physiologically based pharmacokinetic (PBPK) models are sophisticated dosimetry models that offer great flexibility in modeling exposure scenarios for which there are limited data. This is particularly of relevance to assessing human exposure to environmental toxicants, which often requ