β Scribed by Micaela Reddy, R. S. Yang, Melvin E. Andersen, Harvey J. Clewell, III
No coin nor oath required. For personal study only.
A definitive, single source of information on PBPK modelingPhysiologically-based pharmacokinetic (PBPK) modeling is becoming increasingly important in human health risk assessments and in supporting pharmacodynamic modeling for toxic responses. Organized by classes of compounds and modeling purposes so users can quickly access information, this is the first comprehensive reference of its kind.This book presents an overview of the underlying principles of PBPK model development. Then it provides a compendium of PBPK modeling information, including historical development, specific modeling challenges, and current practices for: Halogenated Alkanes Halogenated Alkenes Alkene and Aromatic Compounds Reactive Vapors in the Nasal Cavity Alkanes, Oxyhydrocarbons, and Related Compounds Pesticides and Persistent Organic Pollutants Dioxin and Related Compounds Metals and Inorganic Compounds Drugs Antineoplastic Agents Perinatal Transfer Mixtures* Dermal Exposure ModelsIn addition to pinpointing specific information, readers can explore diverse modeling techniques and applications. An authoritative reference for toxicologists, ecotoxicologists, risk assessors, regulators, pharmacologists, pharmacists, and graduate students in pharmacokinetics and toxicology, Physiologically-Based Pharmacokinetic Modeling compiles information from leaders in the field and discusses future directions for PBPK modeling.
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A definitive, single source of information on PBPK modeling<br> Physiologically-based pharmacokinetic (PBPK) modeling is becoming increasingly important in human health risk assessments and in supporting pharmacodynamic modeling for toxic responses. Organized by classes of compounds and modeling pur
<p><i>Physiologically Based Pharmacokinetic (PBPK) Modeling: Methods and Applications in Toxicology and Risk Assessment</i> presents foundational principles, advanced techniques and applications of PBPK modeling. Contributions from experts in PBPK modeling cover topics such as pharmacokinetic princi
<p>The only book dedicated to physiologically-based pharmacokinetic modeling in pharmaceutical science</p><p>Physiologically-based pharmacokinetic (PBPK) modeling has become increasingly widespread within the pharmaceutical industry over the last decade, but without one dedicated book that provides
The present book describes the methodology to set up agent-based models and to study emerging patterns in complex adaptive systems resulting from multi-agent interaction. It offers the application of agent-based models in demography, social and economic sciences and environmental sciences. Examples
The present book describes the methodology to set up agent-based models and to study emerging patterns in complex adaptive systems resulting from multi-agent interaction. It offers the application of agent-based models in demography, social and economic sciences and environmental sciences. Examples