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Physiologically-Based Pharmacokinetic Model for Trichloroethylene Considering Enterohepatic Recirculation of Major Metabolites

โœ Scribed by Robert D. Stenner; James L. Merdink; Jeffery W. Fisher; Richard J. Bull


Book ID
109157288
Publisher
Springer
Year
1998
Tongue
English
Weight
621 KB
Volume
18
Category
Article
ISSN
1573-9147

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Physiologically Based Pharmacokinetic Mo
โœ R.A. Albanese; H.T. Banks; M.V. Evans; L.K. Potter ๐Ÿ“‚ Article ๐Ÿ“… 2002 ๐Ÿ› Springer ๐ŸŒ English โš– 747 KB

In this paper we present three physiologically based pharmacokinetic (PBPK) models for the systemic transport of trichloroethylene (TCE), with a focus on the adipose, or fat tissue. TCE is a widespread environmental contaminant, and has been shown to produce toxic effects in both animals and humans.