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Physiological Studies of Stress Responses in the Hypothalamus of Vasopressin-Enhanced Green Fluorescent Protein Transgenic Rat

✍ Scribed by M. Shibata; H. Fujihara; H. Suzuki; H. Ozawa; M. Kawata; G. Dayanithi; D. Murphy; Y. Ueta


Book ID
108869807
Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
962 KB
Volume
19
Category
Article
ISSN
0953-8194

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Hypermutation introduces point mutations into the gene segments encoding immunoglobulin variable regions at a rate that is a million-fold higher than the spontaneous mutation rate in most of the genome. Because Ig enhancers are required to target hypermutation, transcription appears to play a critic