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Physiological strains remodel extracellular matrix and cell–cell adhesion in osteoblastic cells cultured on alumina-coated titanium alloy

✍ Scribed by Fabrice Di Palma; Annette Chamson; Marie-Hélène Lafage-Proust; Paul Jouffray; Odile Sabido; Sylvie Peyroche; Laurence Vico; Aline Rattner

Book ID: 108069214
Publisher: Elsevier Science
Year: 2004
Tongue: English
Weight: 616 KB
Volume: 25
Category: Article
ISSN: 0142-9612
DOI: 10.1016/j.biomaterials.2003.09.026

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## Abstract Osteogenic cells from newborn rat calvariae were cultured on titanium surfaces on which cell orientation could be manipulated. Substrata included smooth surfaces and substrata with smooth regions (gaps) flanked by grooves of 47‐μm pitch and 3‐, 10‐, or 30‐μm depth. Orientation angles of