Saposins are small glycoproteins which are required for sphingolipid hydrolysis by lysosomal hydrolases. Each saposin (A, B, C, and D) stimulates a different enzymatic activity. A new simple HPLC method to determine the levels of saposins A, C, and D in tissue was developed. Tissues were homogenized
โฆ LIBER โฆ
Physiological relevance of sphingolipid activator proteins in cultured human fibroblasts
โ Scribed by Farsaneh Sadeghlar; Natascha Remmel; Bernadette Breiden; Ralf Klingenstein; Guenter Schwarzmann; Konrad Sandhoff
- Book ID
- 117456842
- Publisher
- Elsevier Science
- Year
- 2003
- Tongue
- English
- Weight
- 581 KB
- Volume
- 85
- Category
- Article
- ISSN
- 0300-9084
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
Determination of saposin proteins (sphin
โ
Satoshi Morimoto; Yoshimi Yamamoto; John S. O'Brien; Yasuo Kishimoto
๐
Article
๐
1990
๐
Elsevier Science
๐
English
โ 817 KB
Tissue plasminogen activator-induced sec
โ
T.M. Reilly; G. Greenplate; P.B.M.W.M. Timmermans
๐
Article
๐
1989
๐
Elsevier Science
๐
English
โ 557 KB
Evidence for a physiologically active ni
โ
George C. Elliott; Martin C. Rechsteiner
๐
Article
๐
1982
๐
Elsevier Science
๐
English
โ 434 KB
Thrombin regulation of tissue-type plasm
โ
Yumiko Hayakawa; Shigeki Tazawa; Tai-ichi Ishikawa; Kenji Niiya; Nobuo Sakuragaw
๐
Article
๐
1993
๐
Elsevier Science
๐
English
โ 698 KB
Ceramide accumulation is associated with
โ
J. Tohyama; Y. Oya; T. Ezoe; M. T. Vanier; H. Nakayasu; N. Fujita; K. Suzuki
๐
Article
๐
1999
๐
Springer
๐
English
โ 175 KB
Metabolism of GM1ganglioside in cultured
โ
B. Schmid; B. C. Paton; K. Sandhoff; K. Harzer
๐
Article
๐
1992
๐
Springer
๐
English
โ 610 KB
Cultured skin fibroblasts from controls and patients with lysosomal storage diseases were loaded with GM1 ganglioside that had been labelled with tritium in its ceramide moiety. After a 65-h or 240-h incubation, a large percentage of this ganglioside remained undegraded in GM1 gangliosidoses, wherea