To asses the requirement of interleukin (IL)-10 for peripheral CD4 T cell tolerance, the IL-10 knockout (KO) was introduced into a T cell receptor-transgenic mouse model (TCR1) specific for SV40 T antigen (Tag). IL-10-deficient TCR1-transgenic mice failed to establish antigen-specific T cell toleran
โฆ LIBER โฆ
Physiologic regulation of central and peripheral T cell tolerance: lessons for therapeutic applications
โ Scribed by Lequn Li; Vassiliki A. Boussiotis
- Publisher
- Springer
- Year
- 2006
- Tongue
- English
- Weight
- 768 KB
- Volume
- 84
- Category
- Article
- ISSN
- 0946-2716
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