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Physicochemical Properties of Fluorescent Probes: Experimental and Computational Determination of the Overlapping pKa Values of Carboxyfluorescein

✍ Scribed by Aschi, Massimiliano; D’Archivio, Angelo A.; Fontana, Antonella; Formiglio, Alessandra


Book ID
111676394
Publisher
American Chemical Society
Year
2008
Tongue
English
Weight
289 KB
Volume
73
Category
Article
ISSN
0022-3263

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A mixture of cosolvents is described that significantly improves the solubility of most pharmaceutical compounds. The mixture consists of equal volumes of MeOH, 1,4-dioxane, and MeCN, thereby containing polar and nonpolar solvents, and is referred to as MDM (from MeOH, dioxane, and MeCN). MDM is mix