Physicochemical Properties of a New Mult
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Karl J. Box; Gergely Völgyi; Rebeca Ruiz; John E. Comer; Krisztina Takács-Novák;
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Article
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2007
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John Wiley and Sons
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German
⚖ 181 KB
A mixture of cosolvents is described that significantly improves the solubility of most pharmaceutical compounds. The mixture consists of equal volumes of MeOH, 1,4-dioxane, and MeCN, thereby containing polar and nonpolar solvents, and is referred to as MDM (from MeOH, dioxane, and MeCN). MDM is mix