Two 700-ps molecular dynamics simulations of human ␣-lactalbumin have been compared. Both were initiated from an X-ray structure determined at pH 6.5. One simulation was designed to represent native conditions and the other the protein in solution at pH 2.0 without a bound calcium ion. The low pH co
✦ LIBER ✦
Physicochemical properties of blue fluorescent protein determined via molecular dynamics simulation
✍ Scribed by Veera Krasnenko; Alan H. Tkaczyk; Eric R. Tkaczyk; Koit Mauring
- Publisher
- Wiley (John Wiley & Sons)
- Year
- 2008
- Tongue
- English
- Weight
- 462 KB
- Volume
- 89
- Category
- Article
- ISSN
- 0006-3525
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## Abstract The effects of hydrostatic pressure on the structure and stability of porcine odorant‐binding protein (pOBP) in the presence and absence of the odorant molecule 2‐isobutyl‐3‐methoxypyrazine (IBMP) were studied by steady‐state and time‐resolved fluorescence spectroscopy as well as by mol