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Physicochemical Characterization of P760, a New Macromolecular Contrast Agent with High Relaxivity

✍ Scribed by Luce Vander Elst; Marc Port; Isabelle Raynal; Christian Simonot; Robert N. Muller


Publisher
John Wiley and Sons
Year
2003
Tongue
English
Weight
150 KB
Volume
2003
Category
Article
ISSN
1434-1948

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New synthesis of a high molecular weight
✍ Jean-Claude Pierrard; Jean Rimbault; Michel Aplincourt; Soizic Le Greneur; Marc 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 403 KB

## Abstract The new total synthesis in four steps of the compound P1041 is reported. This compound is a high molecular mass ligand (MW 6.32 kDa) derived from dota in which the four substituents are hydroxylated and contain amidic groups. The attribution of the nine protonation constants of P1041 is