Physico/chemical characterization and in vivo evaluation of nanothickness bioceramic depositions on alumina-blasted/acid-etched Ti-6Al-4V implant surfaces
✍ Scribed by Paulo G. Coelho; Jack E. Lemons
- Publisher
- John Wiley and Sons
- Year
- 2009
- Tongue
- English
- Weight
- 479 KB
- Volume
- 90A
- Category
- Article
- ISSN
- 1549-3296
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✦ Synopsis
Abstract
The objective of this study was to physico/chemically characterize and evaluate the in vivo performance of two nanothickness ion beam assisted depositions (IBAD) of bioceramic coatings on implants in a beagle model. Alumina‐blasted/acid‐etched (AB/AE) Ti‐6Al‐4V implants were subjected to two different IBAD depositions (IBAD I and IBAD II), which were physico/chemically characterized by SEM, EDS, XPS, XPS + ion‐beam milling (depth profiling), XRD, AFM, and ToF‐SIMS. A beagle dog tibia model was utilized for histomorphometric and biomechanical (torque) comparison between AB/AE, IBAD I, IBAD II, and plasma‐sprayed hydroxyapatite (PSHA) coated implants that remained in vivo for 3 and 5 weeks. The coatings were characterized as amorphous Ca‐P with high Ca/P stoichiometries with thicknesses of an order of magnitude difference (IBAD I = 30–50 nm and IBAD II = 300–500 nm). The histomorphometric and biomechanical testing results showed that the 300–500 nm thickness deposition (IBAD II) and PSHA positively modulated bone healing at early implantation times. © 2008 Wiley Periodicals, Inc. J Biomed Mater Res, 2009