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Physicochemical and Biological Studies of Inclusion Complex of Methotrexate with β-Cyclodextrin

✍ Scribed by U. V. SINGH; K. S. AITHAL; N. UDUPA

Book ID
118110454
Publisher
Pharmaceutical Press
Year
1997
Tongue
English
Weight
486 KB
Volume
3
Category
Article
ISSN
2042-7158

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The interaction of a nonsteroidal anti-inflammatory drug, naproxen, with \(\beta\)-CD has been studied by several analytical techniques, including 1-D and 2-D proton NMR, fluorescence spectroscopy, and FAB-MS. The negative ion FAB-MS confirmed the existence of a 1:1 inclusion complex of naproxen and