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Physicochemical alterations in blood, cerebrospinal fluid and urine in experimental lactic acidosis in sheep

✍ Scribed by R.C. Patra; S.B. Lal; D. Swarup

Book ID
116052698
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
332 KB
Volume
54
Category
Article
ISSN
0034-5288

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Treatment of lactic acidosis: effects of
Treatment of lactic acidosis: effects of dichloroacetate on lactate and pyruvate levels in the cerebrospinal fluid
✍ I. Okabe; H. Kodama; H. Shimoizumi; S. Kamoshita; S. Miyabayashi πŸ“‚ Article πŸ“… 1986 πŸ› Springer 🌐 English βš– 89 KB

Sir: Dichloroacetate (DCA, 15-20 mg/kg per day) was given orally twice daily to a 12-mouth-old boy with congenital lactic acidosis [1,3]. The clinical and laboratory findings were compatible with Leigh syndrome [2]. Enzyme activities associated with lactate metabolism were normal in his fibroblasts