PHYSICAL SEPARATION OF HEMOPOIETIC STEM CELLS DIFFERING IN THEIR CAPACITY FOR SELF-RENEWAL
โ Scribed by Worton, R. G.
- Book ID
- 125440747
- Publisher
- Rockefeller University Press.
- Year
- 1969
- Tongue
- English
- Weight
- 696 KB
- Volume
- 130
- Category
- Article
- ISSN
- 0022-1007
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Mouse bone marrow cells in suspension were separated into a number of fractions on the basis of cell density by equilibrium density gradient centrifugation, or on the basis of cell size by velocity sedimentation. After each type of separation, the cells from the various fractions were assayed for th
## Abstract We recently identified a murine hemopoietic stem cell colony which consists of undifferentiated (blast) cells and appears to be more primitive than CFUโGEMM in the stem cell hierarchy. The progenitors for the colony which we termed โstem cell colonyโ possess an extensive selfโrenewal ca