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Physical mapping of the major histocompatibility complex class II and class III regions of the rat

✍ Scribed by Lutz Walter; Peter Hurt; Heinz Himmelbauer; Ralf Sudbrak; Eberhard Günther


Publisher
Springer-Verlag
Year
2002
Tongue
English
Weight
190 KB
Volume
54
Category
Article
ISSN
0093-7711

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The BB rat spontaneously develops insulin-dependent diabetes mellitus of autoimmune aetiology. From breeding studies, one of the genes necessary for the development of diabetes in these animals is linked to RT1, the rat's major histocompatibility complex. To study further the RT1 linked diabetogenic