Physical mapping of CSF2RA, ANT3 and STS on the pseudoautosomal region of bovine chromosome X

✍ Scribed by S. S. Moore; K. Byrne; S. E. Johnson; S. Kata; J. E. Womack

• Book ID: 104457398
• Publisher: John Wiley and Sons
• Year: 2001
• Tongue: English
• Weight: 117 KB
• Volume: 32
• Category: Article
• ISSN: 0268-9146
• DOI: 10.1046/j.1365-2052.2001.00740.x

✦ Synopsis

The pseudoautosomal region (PAR) of bovine chromosome X (BTA X) has a particularly low representation of genes and markers, making comparative gene mapping in this region difficult. We describe the localization of three genes__, colony‐stimulating factor 2 receptor alpha__ (CSF2RA), ADP/ATP translocase 3 (ANT3) and steroid sulphatase (STS) on PAR of BTA X using a 5000 rad whole‐genome radiation hybrid panel. The relationship of these genes to a number of previously mapped simple sequence repeat (microsatellite) markers is determined by physical and radiation hybrid mapping methods. The resulting radiation hybrid map resolves a discrepancy between the two major bovine linkage maps in the PAR of BTA X.