Deletion mapping of chromosome region 9p
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Masataka Ohta; David Berd; Masayoshi Shimizu; Hirokazu Nagai; Maria-Grazia Cotti
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Article
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1996
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John Wiley and Sons
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French
⚖ 750 KB
The cyclin-dependent kinase-4 inhibitor gene CDKN2, localized at chromosome region 9 ~2 1 , has been shown to be a familial melanoma gene, though we found that mutations of it are rare in uncultured sporadic melanomas. To determine whether the region of allelic loss at 9p2 I frequently observed in s