Cover Page
Title Page
Copyright Page
Contents in Brief
Contents
Preface
About the Book
Prologue
The structure of physical chemistry
Applications of physical chemistry to biology and medicine
Fundamentals
F.1 The states of matter
F.2 Physical state
F.3 Force
F.4 Energy
F.5 Pressure
F.6 Temperature
F.7 Equations of state
I Biochemical Thermodynamics
1 The First Law
The conservation of energy
Internal energy and enthalpy
Physical change
Chemical change
2 The Second Law
Entropy
The Gibbs energy
3 Phase Equilibria
The thermodynamics of transition
Phase transitions in biopolymers and aggregates
The thermodynamic description of mixtures
Colligative properties
4 Chemical Equilibrium
Thermodynamic background
The response of equilibria to the conditions
Coupled reactions in bioenergetics
Proton transfer equilibria
5 Thermodynamics of Ion and Electron Transport
Transport of ions across biological membranes series
Redox reactions
Applications of standard potentials
Electron transfer in bioenergetics
II The Kinetics of Life Processes
6 The Rates of Reactions
Reaction rates
The temperature dependence of reaction rates
7 Accounting for the Rate Laws
Reaction mechanisms
Reaction dynamics
8 Complex Biochemical Processes
Transport across biological membranes
Enzymes
Electron transfer in biological systems
III Biomolecular Structure
9 The Dynamics of Microscopic Systems
Principles of quantum theory
Applications of quantum theory
Hydrogenic atoms
The structures of many-electron atoms
10 The Chemical Bond
Valence bond theory
Molecular orbital theory
Computational biochemistry
11 Macromolecules and Self-assembly
Determination of size and shape
The control of shape
Levels of structure
12 Statistical Aspects of Structure and Change
An introduction to molecular statistics
Statistical thermodynamics
Statistical models of protein structure
IV Biochemical Spectroscopy
13 Optical Spectroscopy and Photobiology
General features of spectroscopy
Vibrational spectra
Ultraviolet and visible spectra
Radiative and non-radiative decay
Photobiology
14 Magnetic Resonance
Principles of magnetic resonance
The information in NMR spectra
Pulse techniques in NMR
The information in EPR spectra
APPENDIX 1: Quantities and units
APPENDIX 2: Mathematical techniques
APPENDIX 3: Concepts of physics
APPENDIX 4: Review of chemical principles
Data section
Answers to the Odd-Numbered Exercises
Index
PERIODIC TABLE OF THE ELEMENTS