Physical characterization and formulation development of a recombinant pneumolysoid protein-based pneumococcal vaccine
β Scribed by Hu, Lei; Joshi, Sangeeta B.; Liyanage, Mangala Roshan; Pansalawatta, Mekala; Alderson, Mark R.; Tate, Andrea; Robertson, George; Maisonneuve, Jeff; Volkin, David B.; Middaugh, C. Russell
- Book ID
- 118763290
- Publisher
- John Wiley and Sons
- Year
- 2013
- Tongue
- English
- Weight
- 541 KB
- Volume
- 102
- Category
- Article
- ISSN
- 0022-3549
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract ## Background Plasmid DNA (pDNA) vaccines have generated significant interest for the prevention or treatment of infectious diseases. Broader applications may benefit from the identification of safe and potent vaccine adjuvants. This report describes the development of a novel polymerβ
The virulence of many pathogenic Gram-negative bacteria is dependent upon their type III secretion (TTS) systems. Here, we discuss initial formulation studies of five TTS needle tip proteins IpaD (Shigella flexneri), BipD (Burkholderia pseudomallei), SipD (Salmonella spp.), LcrV (Yersinia spp.), and
The adsorption of recombinant botulinum neurotoxin (BoNT) protein-derived vaccine antigens to aluminum salt adjuvants has been previously studied for the development of a trivalent vaccine against the neurotoxins (Vessely et al., in press, J Pharm Sci). The current paper describes an investigation o