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Physical and functional interactions between hematopoietic cell-specific ETS transcription factors and homeodomain proteins

✍ Scribed by Toshiyuki Yamada; Takeshi Shimizu; Takuya Sakurai; Naoki Nanashima; Fumiko Kihara-Negishi; Mitsuhiro Suzuki; Yang Fan; Miki Akita; Tsuneyuki Oikawa; Shigeki Tsuchida


Book ID
104040782
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
871 KB
Volume
33
Category
Article
ISSN
0145-2126

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The human myeloid nuclear differentiation antigen, MNDA, is expressed only in myelomonocytic and a subset of B lymphoid hematopoietic cells. MNDA is uniformly distributed throughout the interphase cell nucleus and associates with chromatin, but does not bind specific DNA sequences. We recently demon