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Physical anchorage and orientation of equine linkage groups by FISH mapping BAC clones containing microsatellite markers

✍ Scribed by G. Lindgren; J. E. Swinburne; M. Breen; D. Mariat; K. Sandberg; G. Guérin; H. Ellegren; M. M. Binns


Publisher
John Wiley and Sons
Year
2001
Tongue
English
Weight
59 KB
Volume
32
Category
Article
ISSN
0268-9146

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✦ Synopsis


A horse bacterial artificial chromosome (BAC) library was screened for 19 microsatellite markers from unassigned or non‐oriented linkage groups. Clones containing 11 (AHT20, EB2E8, HMS45, LEX005, LEX014, LEX023, LEX044, TKY111, UCDEQ425, UCDEQ464 and VIASH21) of these were found, which were from eight different linkage groups. The BAC clones were used as probes in dual colour FISH to identify their precise chromosomal origin. The microsatellite markers are located on nine different horse chromosomes, four of which (ECA6, ECA25, ECA27 and ECA28) had no previously in situ assigned markers.