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Physical analysis of the tuberous sclerosis region in 9q34

โœ Scribed by Chun Y. Zhou; Ke Y. Wu; Margaret A. Leversha; Robert A. Furlong; Malcolm A. Ferguson-Smith; Nabeel A. Affara


Book ID
116154067
Publisher
Elsevier Science
Year
1995
Tongue
English
Weight
433 KB
Volume
25
Category
Article
ISSN
0888-7543

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Tuberous sclerosis (TSC) is a heterogeneous trait. Since 1990, linkage studies have yielded putative TSC loci on chromosomes 9, 11, 12 and 16. Our current analysis, performed on 14 Dutch and British families, reveals only evidence for loci on chromosome 9q34 (TSC1) and chromosome 16p13 (TSC2). We ha