✦ LIBER ✦
Phyllanthoside-Phyllanthostatin synthetic studies. 6. An augmented spiroketalization tactic for the total synthesis of phyllanthocin
✍ Scribed by Amos B. Smith III; James R. Empfield; Henry A. Vaccaro
- Book ID
- 104212346
- Publisher
- Elsevier Science
- Year
- 1989
- Tongue
- French
- Weight
- 250 KB
- Volume
- 30
- Category
- Article
- ISSN
- 0040-4039
No coin nor oath required. For personal study only.
✦ Synopsis
An enhanced spiroketalization maneuver permitting equilibration at both the C(8) and C(11) centers of spiroketals 17a,b leads to a more concise and efficient synthesis of phyllanthocin (i.e., 21 steps, 5.6% overall yield).