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Photosensitizing properties of tin and zinc porphyrin inhibitors of heme oxygenase

✍ Scribed by Nancy L. Greenbaum; Attallah Kappas

Book ID
113385058
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
128 KB
Volume
9
Category
Article
ISSN
0891-5849

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Heme oxygenase-1 (HO-1), an inducible enzyme that catalyzes oxidative degradation of heme to form biliverdin, carbon monoxide and free iron, may protect tumor cells against oxidative stress, thus contributing to rapid tumor growth in vivo. Here, we discuss whether pegylated zinc protoporphyrin (PEG-