Photosensitizing efficiency of two regioisomers of the benzoporphyrin derivative monoacid ring a (BPD-MA)
β Scribed by Anna M. Richter; Ashok K. Jain; Alice J. Canaan; Elizabeth Waterfield; Ethan D. Sternberg; Julia G. Levy
- Book ID
- 115782792
- Publisher
- Elsevier Science
- Year
- 1992
- Tongue
- English
- Weight
- 951 KB
- Volume
- 43
- Category
- Article
- ISSN
- 0006-2952
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The biodistribution of a new and very potent photosensitizer, benzoporphyrin derivative-monoacid, ring A (BPD-MA), was determined in normal and P815 (mastocytoma) or M1 (rhabdomyosarcoma) tumor-bearing DBA/2J mice. A dose of 80 micrograms of 3H-BPD-MA was determined at 3, 24, 48, 72, 96 and 168 h po
Absorption, fluorescence and laser flash photolysis spectroscopies were used to investigate the effects of self-aggregation, binding to human serum albumin and incorporation in cancer cells on the photophysics of benzoporphyrin derivative monoacid ring A (BPDMA). Aggregation of BPDMA has been studie