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PHOTOPHYSICAL STUDIES OF LOCAL ANESTHETICS, TETRACAINE and PROCAINE: DRUG AGGREGATIONS

✍ Scribed by C. J. Mertz; A. D. S. Marques; L. Neil Williamson; C. T. Lin


Book ID
114895773
Publisher
John Wiley and Sons
Year
1990
Tongue
English
Weight
953 KB
Volume
51
Category
Article
ISSN
0031-8655

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Theoretical studies on local anesthetics
✍ Joaquim Delphino Da Motta Neto; Ricardo Bicca De Alencastro πŸ“‚ Article πŸ“… 1997 πŸ› John Wiley and Sons 🌐 English βš– 556 KB

The molecular basis of the pharmacological action of tertiary amine local anesthetics LA is still unclear. However, there is experimental evidence that the LA penetrates into the axon as a neutral form and acts in the charged form from the intracellular phase. In this work we report quantum chemical