With P,-microglobulin-( P2m-) cell lines such as RIE/Db, the surface expression of class I major histocompatibility complex molecules is greatly impaired, and class I molecules that are on the surface are generally misfolded. To determine whether P2m must be continually present with the class I heav
✦ LIBER ✦
Photophysical Analysis of Class I Major Histocompatibility Complex Protein Assembly Using a Xanthene-Derivatized β2-Microglobulin
✍ Scribed by Gakamsky, Dmitry M.; Davis, Daniel M.; Haas, Elisha; Strominger, Jack L.; Pecht, Israel
- Book ID
- 119412296
- Publisher
- Biophysical Society
- Year
- 1999
- Tongue
- English
- Weight
- 161 KB
- Volume
- 76
- Category
- Article
- ISSN
- 0006-3495
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## Objective: Mice deficient in beta2-microglobulin (beta2m), but expressing the human major histocompatibility complex (mhc) class i molecule hla-b27, have been reported to develop spontaneous inflammatory arthritis (sa). we sought to determine whether, under certain conditions, beta2m deficiency
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