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Photon linear attenuation coefficients and water content of normal and pathological breast tissues

✍ Scribed by Jamila S Al-Bahri; Nicholas M Spyrou


Book ID
103990042
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
595 KB
Volume
47
Category
Article
ISSN
0969-8043

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✦ Synopsis


Normal and pathological breast tissue samples were scanned using a Photon Transmission Tomography (PTT) technique in order to determine their averaged photon linear attenuation coefficients (mu). Subsequent to being freeze-dried the samples were examined, using a high purity germanium detector (HPGe) and the gamma-rays of energy 59.5 keV from an americium source, and the results were corrected for the water reduction by the use of the Mixture Rule. The ratio of our experimental findings to the published data for mu for various breast tissues were 88, 96 and 88% for adipose, glandular and tumour tissues, respectively. The mean accuracy in our study, investigated relative to standard chemical compounds, was about 3%. The water content of each tissue type was determined as the weight loss during the freeze drying process. This work was initiated in order to evaluate the suitability of new tissue substitute materials for mammography applications.


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## Abstract In quantitative measurements of the attenuation of ultrasound in 18 samples of variously normal, benign, and malignant breast tissue, we found significantly different ranges of attenuation. As observed in previous __in vivo__ studies, with the exception of medullary carcinoma, malignant