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Photolabile Protecting Groups for Nucleosides: Mechanistic Studies of the 2-(2-Nitrophenyl)ethyl Group

✍ Scribed by Stefan Walbert; Wolfgang Pfleiderer; Ulrich E. Steiner


Publisher
John Wiley and Sons
Year
2001
Tongue
German
Weight
127 KB
Volume
84
Category
Article
ISSN
0018-019X

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Nucleotides, Part LXVII , The 2-Cyanoeth
✍ Claudia Merk; Tilman Reiner; Evgeny Kvasyuk; Wolfgang Pfleiderer 📂 Article 📅 2000 🏛 John Wiley and Sons 🌐 German ⚖ 246 KB 👁 1 views

The amino functions of the common 2'-deoxyribo-and ribonucleosides were blocked by the (2cyanoethoxy)carbonyl group on treatment with 2-cyanoethyl carbonochloridate (5) or 1-[(2-cyanoethoxy)carbonyl]-3-methyl-1H-imidazolium chloride (6) leading to 7, 18, 8, 19, 9, and 20. In 2'-deoxyguanosine, the a