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Photodynamic therapy of human squamous cell carcinoma in vitro and in xenografts in nude mice

โœ Scribed by Dr. Cliff A. Megerian; Syed I. A. Zaidi; Robert C. Sprecher; Sebouh Setrakian; David W. Stepnick; Nancy L. Oleinick; Hasan Mukhtar

Book ID
115044164
Publisher
John Wiley and Sons
Year
1993
Tongue
English
Weight
977 KB
Volume
103
Category
Article
ISSN
0023-852X

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## Abstract Amooranin (AMR), a natural triterpenoid drug isolated and characterized from __Amoora rohituka__ stem bark, is cytotoxic to SW620 human colon carcinoma cell line with an IC~50~ value of 2.9 ฮผg/ml. This novel compound caused depolarization of mitochondrial membrane and decrease of membra