Photodelivery of Nitric Oxide from a Nitrosothiol-Derivatized Surface
✍ Scribed by Etchenique, Roberto; Furman, Melina; Olabe, José A.
- Book ID
- 127128589
- Publisher
- American Chemical Society
- Year
- 2000
- Tongue
- English
- Weight
- 37 KB
- Volume
- 122
- Category
- Article
- ISSN
- 0002-7863
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📜 SIMILAR VOLUMES
## Abstract A new type of nitric oxide (NO)‐releasing material is described that utilizes __S__‐nitrosothiols anchored to tiny fumed silica (FS) particles as the NO donor system. The synthetic procedures suitable for tethering three different thiol species (cysteine, __N__‐acetylcysteine, and __N__
Nitric oxide (NO) is generated in biological systems and plays important roles as a regulatory molecule. Its ability to bind to haem iron is well known. Moreover, it may lose an electron, forming the nitrosonium ion, involved in the synthesis of S-nitrosothiols (SNOs). It has been suggested that S-n