The anti-apoptotic molecules Bcl-xL and
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Verónica Ayllón; Xavier Cayla; Alphonse García; Aarne Fleischer; Angelita Reboll
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Article
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2002
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John Wiley and Sons
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English
⚖ 334 KB
Bcl-xL and Bcl-w specifically interact with PP1alpha and Bad. A phosphatase activity sensitive to okadaic acid was detected in Bcl-xL, Bcl-w and Bad immunoprecipitates. Serine phosphorylation of Bcl-xL and Bcl-w correlates with the number of trimolecular complexes formed. Depletion of Bcl-xL and Bcl