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Photochemical Synthesis of N -Arylbenzophenanthridine Selective Estrogen Receptor Modulators (SERMs)

โœ Scribed by Grese, Timothy A.; Adrian, M. Dee; Phillips, D. Lynn; Shetler, Pamela K.; Short, Lorri L.; Glasebrook, Andrew L.; Bryant, Henry U.

Book ID
126987508
Publisher
American Chemical Society
Year
2001
Tongue
English
Weight
62 KB
Volume
44
Category
Article
ISSN
0022-2623

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Despite the beneficial effects of estrogens in women's health, there is a plethora of evidence that suggest an important role for these hormones, particularly 17beta-estradiol (E(2)), in the development and progression of breast cancer. Most estrogenic responses are mediated by estrogen receptors (E