✦ LIBER ✦

Photochemical properties of water-soluble fluorinated zinc phthalocyanines and their photocytotoxicity against HeLa cells

✍ Scribed by Kaoru Fukushima; Kenji Tabata; Ichiro Okurai

Publisher: John Wiley and Sons
Year: 1998
Tongue: English
Weight: 77 KB
Volume: 02
Category: Article
ISSN: 1088-4246
DOI: 10.1002/(sici)1099-1409(199805/06)2:3<219::aid-jpp66>3.0.co;2-g

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✦ Synopsis

Three types of amphiphilic water-soluble fluorinated zinc phthalocyanines are characterized. They have absorption bands at long wavelength, which cause greater penetration depth of a tissue. The uptake and photodynamic activity of the phthalocyanines against HeLa cells were measured, showing that the phthalocyanines exhibited higher photodynamic activities than zinc tetrasulfonated phthalocyanine.