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Photo-immobilization of epidermal growth factor enhances its mitogenic effect by artificial juxtacrine signaling

โœ Scribed by Guoping Chen; Yoshihiro Ito; Yukio Imanishi


Book ID
117350859
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
177 KB
Volume
1358
Category
Article
ISSN
0167-4889

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โœ Krishnadas Nandagopal; Diana M. Popp; Salil K. Niyogi ๐Ÿ“‚ Article ๐Ÿ“… 2001 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 288 KB

## Abstract The idea of a receptor reserve in mediating cellular function is well known but direct biochemical evidence has not been easy to obtain. This study stems from our results showing that L15 of epidermal growth factor (EGF) is important in both EGF receptor (EGFR) binding and activation, a