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Phostensin caps to the pointed end of actin filaments and modulates actin dynamics

✍ Scribed by Ning-Sheng Lai; Tzu-Fan Wang; Shiu-Lan Wang; Chun-Yu Chen; Jia-yi Yen; Hsien-lu Huang; Chin Li; Kuang-Yung Huang; Su-Qin Liu; Ta-Hsien Lin; Hsien-bin Huang


Book ID
116298955
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
780 KB
Volume
387
Category
Article
ISSN
0006-291X

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Profilin, a ubiquitous 12 to 15-kDa protein, serves many functions, including sequestering monomeric actin, accelerating nucleotide exchange on actin monomers, decreasing the critical concentration of the barbed end of actin filaments, and promoting actin polymerization when barbed ends are free. Mo