Phosphotyrosine-containing proteins in bovine chromaffin cells: Effects of insulin-like growth factor I (IGF-I)
β Scribed by Anne L. Cahill; Robert L. Perlman
- Publisher
- Springer
- Year
- 1991
- Tongue
- English
- Weight
- 709 KB
- Volume
- 11
- Category
- Article
- ISSN
- 0272-4340
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Schwann cells (SCs) are the myelin producing cells of the peripheral nervous system. During development, SCs cease proliferation and differentiate into either a myelin-forming or non-myelin forming mature phenotype. We are interested in the role of insulin-like growth factor-I (IGF-I) in SC developm
IGF-I is mitogenic for the bovine mammary epithelial cell line MAC-T. In addition, IGF-I specifically upregulates IGFBP-3 synthesis in these cells. To investigate this effect on cell growth and IGF-I responsiveness, cell lines were developed that constitutively express IGFBP-3. MAC-T cells transfect
Insulin-like growth factors (IGFs) and IGF binding proteins (IGFBPs) play an important role in cell growth and differentiation. Clinical and epidemiological studies have indicated that measuring IGFs and IGFBPs in blood has potential implications in assessing growth-related abnormalities and risks o