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Phosphoserines of the Carboxy Terminal Domain of RNA Polymerase II Are Involved in the Interaction with Transcription-Associated Proteins (TAPs)

โœ Scribed by Vidyalakshmi, Subramanian; Ramamurthy, Viraraghavan


Book ID
119947517
Publisher
Mary Ann Liebert
Year
2013
Tongue
English
Weight
144 KB
Volume
17
Category
Article
ISSN
1536-2310

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Cdc2 kinase triggers the entry of mammalian cells into mitosis, the only cell cycle phase in which transcription is globally repressed. We show here that Cdc2 kinase phosphorylates components of the RNA polymerase II transcription machinery including the RNA polymerase II carboxy-terminal repeat dom