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Phosphorylation pathways regulate extracellular calcium-induced signal transduction mechanisms in mammalian osteoclasts

✍ Scribed by Aryentino, L.; Colucci, S.; Grano, M.; Barattolo, R.; Zallone, A.Zambonin; Teti, A.


Book ID
122582686
Publisher
Elsevier Science
Year
1992
Tongue
English
Weight
213 KB
Volume
17
Category
Article
ISSN
0169-6009

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## Abstract During bone resorption, osteoclasts are exposed to high Ca^2+^ concentrations (up to 40 mM). The role of high extracellular Ca^2+^ in receptor activator of NF‐κB ligand (RANKL)‐mediated osteoclast survival and their functional interrelationship is unclear. In this study, we show that RA