Phosphorylation of theαsubunit of the sodium channel by protein kinase C
✍ Scribed by Maria R. C. Costa; William A. Catterall
- Publisher
- Springer
- Year
- 1984
- Tongue
- English
- Weight
- 502 KB
- Volume
- 4
- Category
- Article
- ISSN
- 0272-4340
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Incubation of plasma membranes isolated from bovine aorta with either 0.5 mM CaCl2 or with a phorbol ester (1 microM phorbol 12,13-dibutyrate) and phosphatidylserine in an EGTA-containing buffer resulted in the phosphorylation of 10 proteins (Mr of 158, 105, 75, 62, 44, 39, 33, 22, 15 and 9 kDa), pr
## Abstract The cyclic‐AMP‐dependent protein kinase A (PKA) regulates processes such as cell proliferation and migration following activation of growth factor receptor tyrosine kinases (RTKs), yet the signaling mechanisms that link PKA with growth factor receptors remain largely undefined. Here we