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Phosphorylation of pp60src and the cycloheximide insensitive activation of the pp60src-associated kinase activity of transformation-defective temperature-sensitive mutants of rous sarcoma virus

✍ Scribed by Andrew Ziemiecki; Robert R. Friis

Book ID
119010124
Publisher
Elsevier Science
Year
1980
Tongue
English
Weight
966 KB
Volume
106
Category
Article
ISSN
0042-6822

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Phosphorylation of the solubilized insul
Phosphorylation of the solubilized insulin receptor by the gene product of the Rous sarcoma virus, pp60src
✍ Morris F. White; C. Ronald Kahn; Diane K. Werth; Ira Pastan πŸ“‚ Article πŸ“… 1984 πŸ› John Wiley and Sons 🌐 English βš– 720 KB

Both the insulin receptor and the gene product of the Rous sarcoma virus, pp60Src, are protein kinases which phosphorylate themselves and other proteins on tyrosine residues. Addition of the solubilized insulin receptor to purified pp6OSrC increased the phosphorylation of the &subunit of the insulin