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Phosphorylation of p125FAK and paxillin focal adhesion proteins in src-transformed cells with different metastatic capacity

✍ Scribed by Anna Rodina; Kira Schramm; Elena Musatkina; Ernst-Dietrich Kreuser; Armand Tavitian; Alexander Tatosyan


Book ID
117111080
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
114 KB
Volume
455
Category
Article
ISSN
0014-5793

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✍ Daniela Leopoldt; Hal F. Yee Jr.; Enrique Rozengurt πŸ“‚ Article πŸ“… 2001 πŸ› John Wiley and Sons 🌐 English βš– 345 KB

## Abstract Treatment of intact Swiss 3T3 cells with calyculin‐A, an inhibitor of myosin light chain (MLC) phosphatase, induces tyrosine phosphorylation of p125^Fak^ in a sharply concentration‐ and time‐dependent manner. Maximal stimulation was 4.2 ± 2.1‐fold (n = 14). The stimulatory effect of cal