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Phosphorylation of L1-type cell-adhesion molecules – ankyrins away!

✍ Scribed by Kakanahalli Nagaraj; Michael Hortsch

Book ID
113931311
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
167 KB
Volume
31
Category
Article
ISSN
0968-0004

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The L1 family comprises transmembrane cell adhesion molecules of the immunoglobulin superfamily that play an important role in neuronal migration and axon outgrowth, fasciculation, and myelination. Consistent with a crucial role in developmental processes, mutations in L1 cause severe brain malforma