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Phosphorylation of Focal Adhesion Kinase at Tyr397 in Gastric Carcinomas and its Clinical Significance

✍ Scribed by I-Rue Lai; Pei-Yu Chu; Hsiao-Sheng Lin; Jun-Yang Liou; Yee-Jee Jan; Jen-Chieh Lee; Tang-Long Shen

Book ID: 117971206
Publisher: American Society for Investigative Pathology
Year: 2010
Tongue: English
Weight: 702 KB
Volume: 177
Category: Article
ISSN: 0002-9440
DOI: 10.2353/ajpath.2010.100172

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## Abstract The tyrosine kinase Fyn is a member of the Src family kinases which are important in many integrin‐mediated cellular processes including cell adhesion and migration. Fyn has multiple phosphorylation sites which can affect its kinase activity. Among these phosphorylation sites, the serin