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Phosphorylation of CREB, a cyclic AMP responsive element binding protein, contributes partially to lysophosphatidic acid-induced fibroblast cell proliferation

โœ Scribed by Yong-Jun Kwon; Yuanjie Sun; Nam-Ho Kim; Sung-Oh Huh


Book ID
116298174
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
844 KB
Volume
380
Category
Article
ISSN
0006-291X

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## Abstract The role of cyclic adenosine monophosphate (cAMP) is poorly understood in the regulation of normal and abnormal hepatic cell growth. In this study, we examined the regulation of intracellular cAMP levels and its effect on nuclear cAMP responsive elements (CREs) in a rat model of hepatoc