Rap1a activation by CalDAG-GEFI and p38
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Anika Stadtmann; Laura Brinkhaus; Helena Mueller; Jan Rossaint; Matteo Bolomini-
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Article
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2011
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John Wiley and Sons
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English
β 402 KB
Rolling leukocytes are exposed to different adhesion molecules and chemokines. Neutrophils rolling on E-selectin induce integrin a L b 2 -mediated slow rolling on ICAM-1 by activating a phospholipase C (PLC)c2-dependent and a separate PI3Kc-dependent pathway. E-selectinsignaling cooperates with chem