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Phosphorylation of Bcl2 and regulation of apoptosis

โœ Scribed by Ruvolo, PP; Deng, X; May, WS


Book ID
110054860
Publisher
Nature Publishing Group
Year
2001
Tongue
English
Weight
163 KB
Volume
15
Category
Article
ISSN
0887-6924

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BCL-2, a novel regulator of apoptosis
โœ Julie R. Park; David M. Hockenbery ๐Ÿ“‚ Article ๐Ÿ“… 1996 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 573 KB

The bcl-2 gene has a unique function among mammalian oncogenes as a negative regulator of apoptosis. Its expression pattern in embryonic and adult tissues is consistent with a role in maintaining in vivo survival of specific cell types. The biochemical function of bcl-2 is unknown, but its localiza