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Phosphorylation-Dependent Binding of 14-3-3 to the Polarity Protein Par3 Regulates Cell Polarity in Mammalian Epithelia

✍ Scribed by Toby W. Hurd; Shuling Fan; Chia-Jen Liu; Hye Kyong Kweon; Kristina Hakansson; Ben Margolis


Book ID
113558571
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
598 KB
Volume
13
Category
Article
ISSN
0960-9822

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## Abstract **Background:** Recent studies have revealed that aPKC (atypical protein kinase C), PAR‐3 and PAR‐6 play indispensable roles in the regulation of various cell polarization events, from worms to mammals, suggesting that they comprise an evolutionarily conserved protein machinery which is