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Phosphorylation and Regulation of Akt/PKB by the Rictor-mTOR Complex

✍ Scribed by Sarbassov, D. D.


Book ID
118125215
Publisher
American Association for the Advancement of Science
Year
2005
Tongue
English
Weight
305 KB
Volume
307
Category
Article
ISSN
0036-8075

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Ξ²-Catenin is a key protein in the canonical Wnt signaling pathway and in many cancers alterations in transcriptional activity of its components are observed. This pathway is up-regulated by the protein kinase CK2, but the underlying mechanism of this change is unknown. It has been demonstrated that